Posted by Racer on April 4, 2006, at 15:29:26
In reply to What if I didn't wait long enough, posted by Maxime on April 4, 2006, at 14:43:27
Potentially severe acute adverse reaction to a serotonin agonist.
Pathophysiology* excessive stimulation of 5-HT1A and possibly 5-HT2 receptors
* usually result of administration of serotonin agonist to patient who is already receiving a drug capable of potentiating effects of serotoninergic pathways
* may also occur as a result of:
o enhanced serotonin release (eg by cocaine or "ecstasy")
o decreased serotonin re-uptake (eg tricyclic antidepressants)
o decreased serotonin metabolism (eg monoamine oxidase inhibitors)
o excessive adminstration of serotonin precursors or agonists (trazodone, L-tryptophan)Clinical features
Characterized by cognitive and behavioural changes, autonomic dysfunction and neuromuscular abnormalities. Usually develops within hours of administration of precipitating agent.
Cognitive & behavioural changes* confusion
* agitation
* comaAutonomic dysfunction
* hyperthermia
* sweating
* dilated pupils
* tachycardia
* labile BP
* diarrhoeaNeuromuscular abnormalities
* hyper-reflexia
* myoclonus
* shivering
* ataxiaThat's taken from this site:
http://www.aic.cuhk.edu.hk/web8/serotonin%20syndrome.htmAnother:
The symptoms of the serotonin syndrome can include, but are not limited to:* Euphoric feelings
* Drowsiness / Tiredness
* Sustained rapid eye movement
* Overreaction of the reflexes
* Rapid muscle contraction and relaxation in the ankle causing abnormal movements of the foot
* Clumsiness
* Restlessness
* Feelings of being drunk or dizzy
* Muscle contraction and relaxation in the jaw
* Sweating
* Intoxication
* Twitching of the muscles
* Rigidity
* High body temperature
* Mental status changes
http://www.anxiety-and-depression-solutions.com/serotonin-syndrome.htmWhat's going on with you? What are you feeling that makes you worry?
xoxo
poster:Racer
thread:628738
URL: http://www.dr-bob.org/babble/20060403/msgs/628762.html