Posted by linkadge on April 9, 2006, at 19:32:51
In reply to Re: Amisulpride Sucks So Far...., posted by SLS on April 9, 2006, at 18:54:07
I wouldn't think there would be latency either. The rational for this drug strange/mixed. It would not need time to desensitize dopamine autoreceptors like perhaps a MAO-B inhibitor. Wasn't it thought to work as dopamine autoreceptor antgonist ?
The other issue is that, it still is an antipsychotic. I think it has strong antagonistic affinity for D3 receptors (which are heavily located in the neucleus accumbens). So the net effect on dopaminergic neurotransmission, I don't know.
Linkadge
poster:linkadge
thread:630962
URL: http://www.dr-bob.org/babble/20060408/msgs/631115.html