Posted by blueberry on April 17, 2006, at 19:18:40
In reply to Still sluggish and unproductive -- anything help?, posted by Racer on April 16, 2006, at 15:40:40
So sorry Racer. I've thought about it and thought about it. Your situation is puzzling. I remember years ago when prozac and effexor combination worked good for you. I wish our brains would stop readjusting to whatever meds we use.
One thing came to mind though. Whenever I have really overdone it in the dopamine department, I have gotten sluggish and down. Whether it was with drugs, meds, or supplements. A little dopamine for me is good, but a lot does the opposite. Maybe there is just too much dopamine stuff going on.
By the same token, the same applies to norepinephrine. For me anyway. My theory is that when the brain is completely awash in dopamine and/or norepinephrine, the receptors just stop firing. There are a ton of neurotransmitters there, but no activity, no firing. The feedback loop says shut down.
Not sure where to go from here. I know it sounds weird, but I would actually consider reducing the doses slowly. And I know it sounds even weirder, but I might consider something that will block some receptors, like remeron or zyprexa. Yeah, I know they are sedating and gain weight, that's the last thing you want. But when things are working backwards, who knows. Block some receptors to interrupt the feedback loop maybe. Just a weird thought.
poster:blueberry
thread:633891
URL: http://www.dr-bob.org/babble/20060417/msgs/634277.html