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Re: Natural or medicinal 5ht2 antagonist?

Posted by linkadge on April 22, 2006, at 14:41:59

In reply to Re: Natural or medicinal 5ht2 antagonist? » linkadge, posted by blueberry on April 22, 2006, at 13:54:01

I'm not sure of the exact function of the 5-ht1d receptors. I know they have been implicated in OCD, but I think if they're stimulated too much it can contribute to melancholy.

SSRI's directly agonize 5-ht1d and lead to desensitization. There has been talk of adding 5-ht1d antagonists to SSRI's to improve responce.

http://biopsychiatry.com/5ht1dzol.htm

SJW is a good herb. People underestimate it, but it can be very good for anhedonia. Triple uptake inhibitor plus some interesting receptor action. What more could one ask for. I think synthetic SJW is in the pipelines.

Linkadge



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