Posted by blueberry on April 29, 2006, at 10:41:47
In reply to Re: I think Cymbalta is making me depressed » blueberry, posted by yxibow on April 29, 2006, at 0:33:58
Interesting observations. I agree with you about the drug companies covering their butts.
What I don't agree about is the currently accepted explanation that suicide is from a depressed patient getting just enough energy and recovery from a drug to actually carry it out.
They say it is all about chemical imbalance. But not everyone has the same chemical imbalance. Someone who has good serotonin but low dopamine and they start a serotonin med that further squashes out dopamine could feel real bad real fast. And vica versa. It's my own opinion and not scientifically based at all, but I think if a drug affects someone's chemistry in the opposite way that their chemistry needs, then getting more depressed on the drug is not a surprise.
Another theory is that the increased levels of neurotransmitters from a reuptake inhibitor stop the release and firing of presynaptic receptors, which can feel like increased depression to some people, like me. After a few weeks those receptors readjust to the higher levels of neuros and they resume firing at their normal rate. Again though, just an opinion.
poster:blueberry
thread:637749
URL: http://www.dr-bob.org/babble/20060429/msgs/638088.html