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Re: Sustained effect from Dopamine agonists ?

Posted by linkadge on April 30, 2006, at 21:08:08

In reply to Re: Sustained effect from Dopamine agonists ? » linkadge, posted by circusboy on April 30, 2006, at 19:55:07

Yeah, from what I gather ritalin affects the uptake of all three monoamines. Its strongest effect is on dopamine uptake, followed by norepinephrine uptake and then serotonin uptake.

I've heard of some people who find that ritalin is an effective antidepressant.

See my post below on how mice who lack DAT (and consequently have more dopamine) actually perform better in tests for depression than mice who lack SERT (a condition that SSRI's approximate).

Believe it or not, SSRI's are only weakly active in the forced swim test, a mouse model for depressive behavior.


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URL: http://www.dr-bob.org/babble/20060429/msgs/638574.html