Posted by idolamine on May 9, 2006, at 23:05:57
In reply to Adderall and long term brain damage, posted by Pete C. on September 29, 2003, at 13:04:51
I'm suprised no one's posted this yet. Adderall increases extracellular dopamine, as it's supposed to. When this dopamine is eliminated, I believe, by catecholdecarboxylase, it produces chemicals that can oxidize, and then damage, dopamine neurons. It's been a long time since I looked into this, so double check me on ncbi.nlm.nih.gov. Vitamin E and C may help this, though I don't know if vitamin C is permeable to the blood-brain barrier. Also, excitation of dopmaine neurons produces glutamate- which is one of, if the not the main, excitatory chemical produced in the brain. Memantine, or brand name namenda, is a drug used currently for alzheimer's syndrome that normalizes glutamate.
To be honest (I was on adderall at a much higher dosage for a few years), I wouldn't worry. If the adderall is helping you with school, and if you can ask those around you if your behaviour is concerning, and it's not, I'd personally stick with it until school's done and then consider stopping it just to be sure. Just don't go over 40mg if you've just started it and it seems to stop working. James
> Hello,
> I am an adult in college taking 30mg 3 times a day. I recently read an online article saying that studies have found that adderall can destroy some dopimine producors in the brain. Has anyone else read this or know any more about this. The article wasn't clear because it was translated from german. It also said there is a suppliment you could take to help prevent it. Anyone out there know what this might be?
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> Pete
poster:idolamine
thread:264233
URL: http://www.dr-bob.org/babble/20060504/msgs/642011.html