Posted by linkadge on May 20, 2006, at 2:21:35
In reply to Re: Statistical question on SSRIs - ADDENDUM » Squiggles, posted by Larry Hoover on May 15, 2006, at 14:57:10
>If you sample a population enough times, you >can always find a significant result, no matter >how absurd the hypothesis being tested.
>Much of the research that has been published is >not proof of anything at all
I do think that certain clinical trials can help to develop a clearer picture of what the drugs are doing, and the way in which an antidepressant may induce suicidiality. I have actually seen a few clinical trials in which *healthy vaulenteers* were given placebo, or active SSRI. It seemed that the SSRI's were actually producing things like acute apathy, acute akathesia, insomnia, agitation, and suicidal feelings, whereas placebo group experienced no such events.
This is an important type of trial, since in studies such as this we cannot lean back to the old "well this population was depressed anyway".
I have seen reports of psychiatrists self testing SSRI's and having similar findings.
Linkadge
poster:linkadge
thread:640557
URL: http://www.dr-bob.org/babble/20060515/msgs/646149.html