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Re: Do I have tardive dyskinesia or something? » Deneb

Posted by yxibow on June 16, 2006, at 21:26:10

In reply to Re: Do I have tardive dyskinesia or something? » yxibow, posted by Deneb on June 16, 2006, at 17:53:23

> > I would agree its most likely a strong form of pseudoparkinsonism, a form of EPS. Does the intensity get worse if you take your hands and purposely shake them?
>
> I'm not too sure what you mean, but no, the shaking doesn't get worse when I purposely shake them.

I meant really taking your hands and purposely shaking them left and right alot, and then stopping -- this can also illustrate pseudoparkinsonism at least sometimes, because the intense energy simulates activity.

>
> >That would definately be pseudoparkinsonism.
>
> Does pseudoparkinsonism imply tremors that are like the ones in Parkinson's? Tremors in Parkinson's are resting tremors, that is, the tremors occur when the hands/arms/whatever are resting. I don't have that. I have action tremors, most likely a postural tremor. Try pointing your two forefingers at each other, with a tiny space in-between them. When I do that my left hand/arm shakes at times. My right hand isn't shaking now, but sometimes it does.

Action, as in when you are doing certain things? Pseudoparkinsonism is just a way of describing the EPS (which is a way of saying side effects for neuroleptics) that occur with neuroleptics. It doesn't mean that you have Parkinson's although the part of the brain that is affected is one that is affected in Parkinson's. When I was on Zyprexa, or even for some time after, when I would do something like use power tools in the garage or whatever, they would vibrate my hands and eventually there would be a lot of motion.

And yes I have mild side motion (finger V) tremors like you mentioned from Seroquel, those are all forms of tremors/pseudoparkinsonism.

>
> >Arm jerking is a sharp form of it, but it could occur in a variety of ways in different people and different ages I can imagine.
>
> I don't know. I should ask my pdoc about it.

I think that would be a good idea

> > I had it on Zyprexa which was unfortunate because it had helped my disorder more than Seroquel. I still have a slight tremor on Seroquel, but its less than 1Hz.
>
> Did you have resting tremors? Or action tremors?

Both -- more action tremors, if you mean as I was saying, while doing things.

> > When you combine it with the Celexa -- probably not the origin -- the Wellbutrin, well maybe a stimulant in its own right, there could be accumulative interactions I suppose although neither is particularly known for EPS, but SSRIs can give tremor, not called pseudoparkinsonism.
>
> I get sudden jerking motions while on SSRIs. I got them on Zoloft too. They're not that bad. They don't annoy me.

Its possible you're susceptible to the same mechanisms with SSRIs. Zoloft affects dopamine more than other SSRIs.

> > Do you have any propranolol, {Akineton, Artane, Cogentin}, or {Klonopin, Valium, etc.} on hand ? They would definitely slow down something that is pseudoparkinsonism. Even half a dose of OTC Benadryl might slow things down (although make you somewhat drowsy and a little dried out).
>
> My tremors aren't bad enough to bother me all the time. Most days I forget that I even have them. I can do most things without problem. I can even thread a needle. It's things like building a tower out of blocks that I can't do, or playing Jenga.

I can't vouch for the differences between those, everyone's reaction and decision to continue treatment because it affects their lives too much, is something that only you know. If you can thread a needle without much trouble, the tremors are in my opinion not particularly terrible. But they may be bad in yours. Thats why I can't place judgment here and nobody should.


> > If you want to continue the Risperdal, I would definately personally want have a prescription for any of the above.
>
> I do too. Thanks for the information. I didn't know all the drugs that can lessen tremor. Would propranolol help my type of tremor? I've read it helps essential tremor, which is like the tremor I have now.

ET is a disorder that is classically treated with propranolol although other classes of drugs are used too.

> > But since you are experiencing it so severely, I personally, and you and your doctor only know the reasons for it and whether to go on or on, would discontinue it in favour for something less intense like Abilify, Zyprexa, or Seroquel if you need a slight dose of neuroleptic.
>
> I think the only reason why I'm on it right now is because I'm doing very well and we just don't want to change anything.


Then that's a reason to continue as you are going and perhaps get some form of agent that would give more relief to your side effects.


> > TD, though unpredictable, does not show up usually in several months and you are taking a lower dose of Risperdal. If you're really worried about TD, and these are only usually given to people taking full dose neuroleptics, a psychiatrist can give you an AIMS exam which is just a few questions and probing you for some muscle demonstrations. They're normally only given every six months typically.
>
> I'll ask my pdoc whether or not I need such a test.
>
> Thanks for your reply. It was very informative.
>
> Deneb*


No problem. AIMS exams aren't usually given that often at low doses of neuroleptics but your doctor may bother to do so if you wish, its just a few minutes really.


 

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poster:yxibow thread:657326
URL: http://www.dr-bob.org/babble/20060610/msgs/657832.html