Posted by pulse on June 27, 2006, at 15:25:41
In reply to Do many people find TCA's better then SS/NRI's?, posted by FrequentFryer on June 22, 2006, at 21:44:16
yes, i do (did, see below). only sinequan (doxepin, asendin) ever gave me a robust full remission, sustained for yrs. w/no increase in dosage.
the GI SEs of nausea and constipation, back then, in my late 20's (now in 50's) were something i could easily endure, until it worked at exactly 3 wks.
however, since my mis-dx of bipolar for 9 yrs. in 1990, all the mood stabilizers i never needed in 1st place, caused me to acquire very bad reflux/ gerd, requiring proton pump inhibitors (prilosec, then prevacid, finally at highest dose).
now, 16 ys after that mis-dx, i'm stuck on the ppis (common), & the sinequan constipation now increases the reflux, as well. i've tried sinequan 3 times in these recent yrs., & can't overcome.
if you've either iron guts or aren't prone to GI probs, you'd manage fine.
someone - linkage? - correct if wrong - tcas aren't useful for those with atypical depression (over-eating & sleeping, etc.)
tcas cause weight gain for most, but for me much less than remeron. i needed gain, so sinequan was good. gain stopped & never increased when i reached a healthy weight (still slim). intitial cravings for sweets, but this stopped early, never to return.
nortiptyline & desipramine least gainers, but desip. is less balanced w/mostly just norepinephrine affected.
pulse
poster:pulse
thread:660343
URL: http://www.dr-bob.org/babble/20060623/msgs/661878.html