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Re: Effexor - A personal experience (long read)

Posted by silvercoin on July 26, 2006, at 16:58:14

In reply to Effexor - A personal experience (long read), posted by Myrk on July 26, 2006, at 14:25:37

Sometimes Effexor and other drugs that increase serotonin transmission can actually worsen OCD issues even though they a first line treatment for this disorder. My guess is that perhaps non-therapeutic serotonin receptors are being stimulated, such as the 5-HT2a receptor, and this may cause or worsen a problem in susceptible individuals. Theoretically, adding an atypical antipsychotic might help alleviate the problem if this line of reasoning actually has any merit, as these drugs blockade the 2a receptor. Probably better to just discontinue the offending agent as you did if the therapeutic benefits are limited or nonexistent anyway.

Todd


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