Posted by C5 on July 28, 2006, at 9:59:53
In reply to Re: Valproate + Lamictal for BP2-doses, posted by SLS on July 28, 2006, at 9:51:37
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> Generally speaking, you go with the dosage of Valproate that you think is best according to your doctor's experience and cut the dosage of Lamictal in half. If the target dosages of each drug separately would be Depakote 1500mg and Lamictal 200mg, the combination would result in dosages of:
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> Depakote 1500mg + Lamictal 100mg
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> If you are taking Depakote at the same time, you would need to start the Lamictal at a low dosage and raise it gradually to avoid provoking a dangerous rash reaction:
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> 12.5mg x 2 weeks
> 25mg x 2 weeks
> 50mg x 1 week
> 100mg
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> * For the first 2 weeks, the current package insert says to take 25mg every other day. The original package insert said to take 12.5 each day. I don't know why the change was made.
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>
> - Scottthanks Scott for your prompt reaction ;
I have well understood your point as far as the Lamictal doses are concerned,but a little bit surprised about the dose exemple you have provided for the Valproate,as I am on just 600mg Orfiril(Long) known to be a "typical" dose for a soft bipolarity(Cyclothimia)?! what is your opinion? does it seem to you being too low?
poster:C5
thread:671379
URL: http://www.dr-bob.org/babble/20060724/msgs/671388.html