Posted by linkadge on August 29, 2006, at 16:47:41
In reply to Dopaminergics-addiction-Not nesserilly, posted by Tom Twilight on August 29, 2006, at 1:51:31
>Sadly reasoning like Linkadges has produced a >phobia of dopamine drugs.
I am not against dopaminergically based medications at all. Please feel free to read all of the posts in this thread to see that I too believe that this is a very usefull avenue for future drug development.
For some people ADHD continues into adulthood, and for some people it does not. Just like how depression can be a one time thing, or it can be a chronic disorder.
I totally agree, it does depend on the part of the brain that the drug activates. It is possable to rase dopamine in motivation circutry without directly affecting reward circutry.
Not everybody gets addicted to stimulants I agree. There are many factors, duration of treatment being one.
If you give a mouse ritalin, for instance, through its childhood, and then discontinue the drug in its adulthood, it develops significant indications of reward deficit. Simply meaning, the rat becomes abnormally anhedonic for the rest of its life. That is because its brain has worked to accomidate the drug. I will look for that study.
Drugs like ritalin and amphetamines do turn on the same addiction genes as harder drugs, that is the truth. There is a risk, wheather you succumb to addiction or not. Drugs like straterra, do not however.
That is not to say that all dopaminergic medications activate such genes.
Linkadge
poster:linkadge
thread:680536
URL: http://www.dr-bob.org/babble/20060825/msgs/681245.html