Posted by SLS on September 3, 2006, at 7:28:37
In reply to Can Buspar worsen anxiety?, posted by Shell on September 2, 2006, at 23:47:47
> My anxiety has become markedly worse in the last month. I now have daily episodes where I become short of breath and my chest gets tight, which I almost never had before. My pdoc told me it was a fairly common reaction to Buspar -- some people actually experience an increase in their anxiety while taking it. He told me to stop taking it and that the anxiety should go back to at least my pre-Buspar levels.
>
> Has anyone else had this experience with Buspar? I don't remember reading anything about it and can't find anything online about increased anxiety as a side effect.
Buspar is metabolized into a substance called 1-PP. This metabolite acts very much like Remeron in that it is a NE alpha-2 antagonist. It can increase the amount of norepinephrine synthesized and released by neurons. For some people, this produces anxiety and can actually worsen depression in some cases.
- Scott
poster:SLS
thread:682532
URL: http://www.dr-bob.org/babble/20060901/msgs/682598.html