Posted by Donna Louise on September 18, 2006, at 20:28:15
In reply to Re: discontonuimg Emsam, posted by willyee on September 18, 2006, at 20:13:06
> > You think denepryl is really not great for chronic use? Do you have any info/articles about this?
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> No the opposite actualy,i foolow a group called smart drugs and nutrients,which speaks on the use of both drugs and nutrients and importance of both.
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> In the book titled actualy so,part two,there is an entire chapter on deprenyls use for depression,there it speaks on the low dosage used for depression.
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> Also following the group it was just a drug known to be used sparingly since it had such a imapct on dopamine specifcaly.
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> I can only speak from my own usage,and my worry was the more specific direct impact on dopamine as opposed to all the chemicals that dopamine seemed to work on.
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>
> Deprenyl was a parkinson disease drug,as well as recomended for smoking cessation because of its impact on dopamine,i have heard the dose increase would change that more however it still concerned me,having it used it myself i could feel the dopamine accumaltion and the side effects that would occur.
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> I dont discourage anyone from it though,its new,novel,fairly safe,in fact i told a specific person im not sure why they are waiting so long to try it,everyone is different and the only sure thing is to try it urself.
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> I having used it was just offering advice on tapering down since i had to do so myself.
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> I hardly ever discourage anyone from seeking help,seeking alone shows you are willing to keep trying.
>
>The big appeal to me that the patch offered was bypassing first pass metabolism so much more of the parent compound was available and much less of the amphetamine metabolites than with oral route. Theoretically, these patches are non selective and should deanimate serotonin and norepinephrine as well as dopamine, as only dopamine is deanimated with the oral selegiline at the low mg. So I am suprised to find it still so activating,. I am liking and needing the activation, that isn't the problem, is just does not seem to working as an AD for me and has made all these soft bipolar nightmares very apparant. But that is just me. I had a good day today except for the meltdown in the middle of the day. Cycling? just insufficiently treated? All I know is if it works like I would think it should, it would be an awesome drug. so like Willyee says, try it, it could be the best thing you have had yet.
Donna
poster:Donna Louise
thread:686465
URL: http://www.dr-bob.org/babble/20060909/msgs/687205.html