buspar properties; gepirone available anywhere?

Posted by iforgotmypassword on September 25, 2006, at 15:50:39

(NOTE: *NOT* asking how to get an unapproved med; simply asking if it is technically-speaking available anywhere.)
buspirone seems odd in its dopaminergic effects, specifically anti-dopaminergic effects. it seems to be well known as a D2 blocker. but it may also be a PRESYNAPTIC dopamine AUTOreceptor AGONIST, which is even spookier.
it also may be indirectly anticholinergic. (whew!)
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=6123570&query_hl=26&itool=pubmed_docsum
buspirone at high dose worsens parkinson's symptoms.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=3026624&query_hl=26&itool=pubmed_docsum
this is awkward... i want to try low doses anyway, but given how i get the extrapyramidal pseudoparkinsonian signs from SSRIs and even spontaneously (may be a lyme effect) i worry heavily.
i also am a hoarder, and have severe apathy/amotivation/concentration problems so anticholinergic effects scare me that way too.
gah.
anyone have any NEW news on gepirone? any new signs of life?

Thread

buspar properties; gepirone available anywhere? iforgotmypassword 9/25/06
arg. sorry for being messy. iforgotmypassword 9/25/06
Re: arg. sorry for being messy. linkadge 9/25/06
Re: buspar properties; gepirone available anywhere » iforgotmypassword yxibow 9/27/06
Re: buspar properties; gepirone, prx 00023 psychobot5000 9/28/06
Re: buspar properties; gepirone available anywhere iforgotmypassword 10/1/06

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