Posted by SLS on October 4, 2006, at 0:44:21
In reply to SLS, posted by bipolarspectrum on October 4, 2006, at 0:05:19
> SLS,
> Have you considered T4?? I personally vouch that it has psychotropic activities... I'm not claiming that it will cure you but I definately think its worth a shot.. it could be a powerful augmenting agent...Good idea.
I may revisit T4. I tried it once in combination with Parnate + desipramine + amphetamine. I felt a mild improvement. Because it was insufficient, I discontinued it, but perhaps it would be more helpful now since I am taking different medication. Also, my TSH is greater than 5.0.
> also, have u tried folic acid? zinc? High dose Vit C?
Yup. Yup. Yup.
> these have all sent me manic,
Man, you sure are sensitive. What does magnesium or taurine do for you?
One doctor that I saw not too long ago had a treatment-resistent rapid-cycling bipolar patient who responded to Keppra monotherapy.
- Scott
Epilepsy Behav. 2004 Dec;5(6):1017-20. RelatedMonotherapy treatment of bipolar disorder with levetiracetam.
Kaufman KR.
Department of Psychiatry, UMDNJ-Robert Wood Johnson Medical School, 125 Paterson Street, Suite 2200, New Brunswick, NJ 08901, USA. kaufmakr@umdnj.edu
Bipolar patients with early-onset, comorbid substance abuse, rapid cycling, and mixed episodes are difficult to treat and frequently require rational polypharmacy. When polypharmacy is unsuccessful, the clinician must consider the off-label use of newer psychotropics. Levetiracetam is a novel anticonvulsant with antikindling, inhibitory, and neuroprotective properties that is effective in an animal model of mania. This case report describes a patient with treatment-resistant rapid cycling bipolar disorder who failed 15 psychotropics, individually or in various combinations (maximum of 6), but ultimately responded to levetiracetam monotherapy and remained without bipolar features during 1 year of maintenance treatment, excluding 1 week during which the patient was medicine noncompliant. Further, methylphenidate used to treat comorbid attention deficit disorder did not precipitate manic features. Levetiracetam should be further studied for its potential use in the treatment of bipolar disorders.
Publication Types:
* Case Reports
PMID: 15582854 [PubMed - indexed for MEDLINE]
poster:SLS
thread:690991
URL: http://www.dr-bob.org/babble/20061003/msgs/691700.html