Posted by SLS on October 8, 2006, at 15:22:07
In reply to Re: HELP, posted by fca on October 8, 2006, at 12:01:18
Hi.
> Two of the leading pdocs on OCD in the country are using Namenda for TX resistant OCD and report (online) good anecdotal results.
Not meaning to be challenging, but I wouldn't mind reading some of their work. Would you mind naming them?
> Besides it is relatively benign as far as psychotherapeutics go.
I had no side effects at all except for that feeling of intoxication when I tried to increase to 40mg. Perhaps that would have dissipated had I continued with it.
> I do not believe effexor or any of the other SNRIs are particularly helpful with OCD.
There is clomipramine (Anafranil). That's an SNRI, and is probably the most effective drug currently available for OCD. Is there any reason to make a generalization like that? Do you feel NE reuptake inhibition is counterproductive?
The only other two SNRIs are Effexor and Cymbalta. The other tricyclics really don't qualify I don't think.
Not too many studies have been conducted with Effexor in the treatment of OCD from what I could find. Most have been favorable. One placebo controlled study was not. One found Effexor to be helpful to treat SSRI non-responders. However, there was one VERY good study that compared Paxil to Effexor in which Paxil was shown to be superior. I thought the study was of an impressive design and used the right dosages and an adequate treatment duration.
I guess your recommendation of trying the Namenda makes sense. Did those doctors give any indication as to how long to allow Namenda to work?
When thinking of Effexor, my focus was on the depression, the two anxiety disorders, and the lack of treatment response to Paxil. I guess the OCD didn't jump out at me as a prominent feature of the overall situation.
BIGDaddy:
How does your OCD present itself?
- Scott
poster:SLS
thread:692628
URL: http://www.dr-bob.org/babble/20061003/msgs/693067.html