Posted by yxibow on October 30, 2006, at 17:14:11
In reply to Re: way I feel I'd volunteer for LD 50 (double bli » ronaldo, posted by Lindenblüte on October 30, 2006, at 11:09:05
> I bet it varies widely, especially for us humans. Rats and mice are usually all so inbred. Often a study just tests a single strain of rats.
While surprisingly little creatures, for LD50 testing they are (and this is coming from a vegetarian) cheap and "lower on the food chain" than killing dogs with substances (which is done, but much less thankfully) and share certain base primal brain features with humans. We're not talking a few animals, but dozens tested at doses that would floor a human in terms of relative weight.
This isn't just for medications, hardware/paint products, industrial chemicals, etc, have all been challenged if they're going to be in an OSHA setting.
The one thing that I disapprove is rampant wholesale testing for cosmetics, which except for certain situations (dermatological medications and things used in reconstructive surgery, etc.), is not a necessity for life. But that's just my soapbox. Also a lot of OTC lotion ingredients, e.g., have already been tested anyhow and are considered GRAS (generally recognized as safe) by the FDA.-- tidings
Jay
poster:yxibow
thread:698250
URL: http://www.dr-bob.org/babble/20061028/msgs/699110.html