Posted by zeugma on November 1, 2006, at 5:42:25
In reply to Re: effect of melatonin on seratonin? » zeugma, posted by johnnyj on October 31, 2006, at 20:35:54
> Thank you >>
you're welcome.
I will ask my doc about the melatonin issue. Even if luvox makes blood levels higher would light in the morning tone this down? Before meds I slept great and used to take a while to get going in the morning. >>
I'm not sure about morning light effect with Luvox. I mean, i have absolutely no idea. I was prescribed a light box years ago, and the problem was, in two words, noncompliance and misdiagnosis. I was already developing narcoleptic symptoms, which are accompanied by migraine-like headaches, photophobia (which made me averse to sitting under the box for an hour), etc., (although they are more shortlived than most migraines) and the interference in my sleep was related to this, and morning light probably (I only say this because I wake up early nowadays, am exposed to daylight, but it doesn't help. At all.) is not the right tx for this.
>
> Do you think that luvox is, how should I say, harmful overall? What about long term effects of increased melatonin on the circadian rythm? I know things are out of whack right now to a degree.>>I don't know. There is probably a genotype influence as well, which is useless at the moment since there is no protocol as far as I know for this, except in experimental studies.
luvox is also a sigma-1 agonist, but so far, beyond reversing PCP effects in rats, little is known about this effect: it is one of those 'theoretical' AD effects that have not been demonstrated in the clinic.
>
> I have ocd, anxiety issues and this results in a depressive state to some degree. I thought luvox might be a good choice as I really don't get tired and sleepy like I normally used to and that is what I need to feel better...sleep.
>Luvox is considered sedating for an SSRI. But it is simply impossible to predict what will happen. Luvox is more prone to melatonin-related s/e than other SSRI's, but I don't know to what extent that causes the 'sedation' that is observed with Luvox administration.
>
So, I may try to wean off even thought I am not sure how to do this cold turkey as I might feel better quicker but not sleep better. Of course my pdoc will approve any of this.>>good. the issue has come up of posters dispensing advice without qualifications, and I have none. I have read a lot about sleep disorders and their treatments because I have suffered from them, and I have discussed these matters with sleep specialists. When I asked point blank about whether or not Lexapro was good/bad for sleep disorders, (as I wrote in my post to phillipa) she simply said the effects were variable. I wouldn't take melatonin or Rozerem on Luvox, but the Rozerem ads on the radio advise against this, too, and I assume they have good reason to do so.
-z
>
>
poster:zeugma
thread:699037
URL: http://www.dr-bob.org/babble/20061028/msgs/699510.html