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Re: MAO EXPERTS/USERS...Recommendations??????

Posted by stargazer on November 12, 2006, at 16:13:26

In reply to Re: MAO EXPERTS/USERS...Recommendations??????, posted by josephine grandoni on November 12, 2006, at 13:53:15

J,

I don't know anything about the other drug you take (Naltrexsone). I looked it up and wasn't sure what type of drug it is. Is it an antidepressant? Are you in the US or outside of the US? Some of the people on this website are from outside the US and the meds they take are different than the ones available in the US so occasionally the names are not familiar to me.

There are two types of MAO (monoamine oxidase), A and B, enzymes which breakdown certain neurotransmittors, including dopamine, norepinephrine and serotonin. I believe the types differ by where they are located in the body. I believe A is in the stomach, while B is in the Brain (CNS). The drugs typical for depression (Nardil, Parnate and Marplan) inhibit the MAO-A enzymes. The newer MAO drug, Ensam, affects the MAO-B enzyme. I don't really understand the significance between the A and B enzymes. It's quite confusing for a layperson, so other people can usually explain this stuff better to the rest of us, as long as they keep it simple.

I know Ensam has none of the dietary restrictions of the MAO-A drugs which is a huge advantage and is a patch, not an oral, form.

SG


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URL: http://www.dr-bob.org/babble/20061110/msgs/702918.html