Posted by linkadge on November 25, 2006, at 14:55:17
In reply to Re: FYI...Thought this was sad and funny » BUCKEYE FANATIC, posted by Racer on November 25, 2006, at 13:17:50
The actions of methylphenidate on serotonin are weak and do not fully explain its effects in ADHD. If the actions of methylphenidate were serotonergically mediated, then one would exect SSRI's to produce a similar calming effect in ADHD which they do not.
SSRI's often make ADHD worse.
Methylphenidate has negligable effect on the serotonin reuptake pump, but significant affinity for the dopamine reuptake pump. So if it affects serotonin, I don't know how.
Linkadge
poster:linkadge
thread:707054
URL: http://www.dr-bob.org/babble/20061123/msgs/707135.html