Posted by SLS on January 15, 2007, at 5:34:49
In reply to Re: Can Someone Explain Providgil So many Different Re, posted by blueberry1 on January 15, 2007, at 5:02:23
Provigil was accidentally labeled a NE alpha-1 agonist based on some errant results of an early study.
The drug seems to:
1. Enhance hypocretin neurotransmission, particularly in the hypothalamus. This is probably the mode by which it promotes wakefulness.
2. Glutamate release. This might be responsible for its mood-elevating and motivational properties.
- Scott
poster:SLS
thread:722202
URL: http://www.dr-bob.org/babble/20070113/msgs/722438.html