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Re: amineptine/tianeptine for depression

Posted by sukarno on January 16, 2007, at 22:56:06

In reply to Re: amineptine/tianeptine for depression » psychobot5000, posted by liliths on January 16, 2007, at 7:06:17

Hi again. :-)

I never experienced any weight gain on tianeptine. If anything, in the first few weeks it reduced my appetite slightly. Weight gain is definitely not a side effect listed in the pamphlet that comes with Stablon.

It's just one person here who reported they gained weight, and even then, it's hard to determine cause and effect. It's just anecdotal. :-) Someone might not eat much when they are depressed and when they take any antidepressant, they'll eat more when they feel better. That could explain the weight gain.

If I am severely depressed, I won't want to eat much of anything. Some people eat more when they're depressed (especially carbohydrates) and then eat less when the antidepressant starts working.

In theory, tianeptine should not cause weight gain, since it gives dopamine a slight boost in the nucleus accumbens and frontal cortex. SSRIs, on the other hand, antagonize (reduce) dopamine and are linked to weight gain, even though they can actually reduce the appetite. Antipsychotics are notorious for causing weight gain since their principal action is that of a dopamine antagonist.

I don't think it will be a problem. I think it won't affect your weight one way or the other. :-)


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URL: http://www.dr-bob.org/babble/20070113/msgs/723050.html