Posted by yxibow on January 17, 2007, at 22:50:59
In reply to Re: Are higher doses of seroquel LESS sedating? » Quintal, posted by Phillipa on January 17, 2007, at 19:51:56
> Q oh anxious. That's a fact. Give me an hour in the late am (sleep late and go to bed late) and I gotta go somewhere anywhere and then boom I'm so tired in a couple of hours. Any idea why? Love Phillipa
Altering your sleep cycle so that you stay up late and go to bed late, and possibly nap during the day can contribute to a complete disruption of circadian rhythm. I can attest that when I stay up late for no particular reason other than I want to play with the computer, even if I get my usual paltry 7 hours of sleep, my daily rhythm has already changed.And I don't recall offhand, but for every hour you change your sleep cycle, it takes so many hours and so many days to change. As humans we have approximately a 24 hour cycle, actually it exceeds 24 hours by approximately half an hour depending on genetics.
This is one of the reasons people sometimes take melatonin to reset their clock (or Rozerem which is much more powerful than melatonin itself).
I guess in a way, ending the day earlier than I feel is normal is like saying goodbye to another day of life. But another way of looking at it, is that if you go to sleep earlier, you actually have the daytime (especially in winter) to utilize, and you're up when most of the rest of the population is.I know its connected to my fear of death which is just another part of the life cycle if you look at it that way but being agnostic and also having depression doesnt quite settle the concept for me. It is one if not the core issue that centers my anxiety.
But as for the original -- yes, small doses, any dose really of Seroquel, one can become use to the sedation somewhat, but I don't think nearly as fast as habituation to Trazodone.
The comment on Phenergan is probably on the nose -- I would say that if I "stayed up" for the Seroquel and I was hungry, I would attempt to eat possibly, but due to the way Seroquel affects my swallowing mechanism when it first comes on, is mildly dangerous, because you're downing a sandwich from the fridge and you're tired and crashing into things, and you can't swallow properly.I guess its all in the timing.
Seroquel also doesn't really change a plugged nose for me in the morning -- Claritin might -- but maybe I've become used to part of the antihistamine effect or maybe it really doesn't touch the "seasonal allergy" part, although you'd think a massive pie chart with H1 taking up like half of it would do so. Genetics? Who knows.
-- tidings
poster:yxibow
thread:722520
URL: http://www.dr-bob.org/babble/20070113/msgs/723461.html