Posted by Jimmyboy on January 20, 2007, at 18:16:43
In reply to Re: Finally found something that works! for me! » Jimmyboy, posted by blueberry1 on January 20, 2007, at 12:54:13
Hey Blueberry,Sorry to hear that things are so horrible for you. This affliction we have is painful, lonely and invisible to most people around us.. what a sh*tty combination. I hope the remeron brings you some relief. Peace brother.
PS - Oh yeah I have been taking the zinc b/c I read this - plus , its cheap and harmless as far as I can tell.
1: Eur J Pharmacol. 2004 May 10;492(1):57-9. Links
Zinc treatment induces cortical brain-derived neurotrophic factor gene expression.Nowak G, Legutko B, Szewczyk B, Papp M, Sanak M, Pilc A.
Institute of Pharmacology, Polish Academy of Sciences, Smetna 12, PL 31-343, Cracow, Poland. nowak@if-pan.krakow.plMost of antidepressants induce expression of the gene coding for brain-derived neurotrophic factor (BDNF) in the hippocampal/cortical neurons. Recent data indicate antidepressant-like activity of zinc in animal models. We now report that chronic treatment with zinc induced an increase in cortical but not hippocampal BDNF mRNA level (Northern blot). Tranylcypromine, a classic antidepressant, increased BDNF mRNA level in both examined brain regions. This is the first demonstration that zinc increases the BDNF gene expression, which is the effect shared by most of clinically effective antidepressants.
PMID: 15145706 [PubMed - indexed for MEDLINE]
poster:Jimmyboy
thread:723977
URL: http://www.dr-bob.org/babble/20070119/msgs/724574.html