Posted by yxibow on February 6, 2007, at 20:05:40
In reply to Re: Propranolol and hallucinations?, posted by halcyondaze on February 6, 2007, at 15:38:26
> There are actually several reports in the literature about this:
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> << http://www.jonmd.com/pt/re/jnmd/abstract.00005053-199803000-00010.htm;jsessionid=FL0KWhXPNrlfqWRnxg1hCbnztqJQpQzNqFnSrLqzvrRzZv1fZLtL!1538755720!-949856144!8091!-1 >>
>
> << http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=7065308&dopt=Citation >>
>
> << http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&list_uids=5781495&dopt=Citation >>
>
> << http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?itool=abstractplus&db=pubmed&cmd=Retrieve&dopt=abstractplus&list_uids=6745087 >>
>
> << http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=638680&dopt=CitationThis study appears to associate it mostly with hypnaegogic / hypnapompic wake to state situations, especially in conjunction with alcohol.
>
> << http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?itool=abstractplus&db=pubmed&cmd=Retrieve&dopt=abstractplus&list_uids=1120173 >>
>
> << http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?itool=abstractplus&db=pubmed&cmd=Retrieve&dopt=abstractplus&list_uids=638680 >>
All of the other studies were far to old to draw anything other than summary, and all were case reports. It is a rarity I would have to conclude.And at 30mg slightly above the noise level in the one study that could be drawn out.
That doesn't mean that you are a case report of visual hallucinations but it may be a reaction with other medications.
You could ask your psychiatrist to switch you to pindolol or another non-cardioselective beta blocker to see if it disappears.
As far as akathisia, racing pulse, or especially pseudoparkinsonism, I've generally not seen any results until 80mg, but my liver seems to eat medications for breakfast. Who knows, I'm probably a fast metabolizer.
Anticholinergics are generally better for central movement conditions but I would try some of the other beta blockers if your doctor is up to it. Anticholinergics will almost always have some visual effects, though, caused by the atropine like alkaloids -- usually mild, but depends on the person, a general sense of brightness due to dilated pupils.
Sorry to hear that your trial with propranolol has gone a bit awry. But it should dissipate with discontinuation -- some of the subjects in the study that I was able to read did associate the hallucinations with fear but I don't think that it is something that one should worry in the long term at a low dose such as that.The trails, you're seeing are palinopsia.
Hope that helps-- Jay
poster:yxibow
thread:730407
URL: http://www.dr-bob.org/babble/20070201/msgs/730600.html