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Re: DEPAKOTE - positive experiences + how long?

Posted by blueberry1 on February 7, 2007, at 19:30:41

In reply to DEPAKOTE - positive experiences + how long?, posted by chiron on February 7, 2007, at 9:44:11

I can't speak for depakote alone because when I tried it at 500mgER I was also on 5mg zyprexa and 25mg zoloft.

I had immediate antidepressant action in 24 hours. Best I had felt in a very long time. For the next month I commented in my notes "not depressed, just blah". But I've been blah with all meds. Being not depressed was more of a blessing than I had realized at the time now that I look back on it.

While weaning off depakote because I didn't think it was doing anything I ended up in the emergency room in a crying sobbing despair crash. Felt like a dopamine crash like the comedown after cocaine or amphetamines. They told me to go home and take my depakote. Not within 24 hours, but within 48 hours I was back to being undepressed and blah again.

I tried depakote by itself since then. First few hours I felt a soft warmth comfort mood lift. Again the second day. The third day I could feel my depression was getting a lot worse and it scared me away. Felt better after I stopped it. I think somehow depakote works in combination with antidepressant or antipsychotic but not by itself, for depression. Except, there was someone here a while back that was depression cured with 2500mg depakote.

Strange thing though. While it is supposed to be good for anxiety, I actually had my anxiety increase a notch while on it.


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