Posted by iforgotmypassword on February 10, 2007, at 21:21:10
wikipedia:
"Amantadine has been associated with several CNS side effects, including nervousness, anxiety, agitation, insomnia, difficulty in concentrating, and exacerbations of pre-existing seizure disorders and psychiatric symptoms in patients with schizophrenia or Parkinson's disease. This is due to the fact that Amantadine possesses significant anticholinergic activity."
sounds very dubious, i don't know where they got this, especially the rationale that anticholinergic activity causes these side-effects. tho, as a coincidence is amantadine anticholinergic and would memantine be too? does it say anywhere that amantadine is anticholinergic and they may have elaborated inaccurately based on that?
i have this awful feeling i should have tried amantadine first instead of memantine. given how much my problems relate to a tardive akithisia like syndrome, apathy, etc. NMDA-antagonism is primarily what i am looking for tho... still amantadine would have been covered and saved me money. who knows how my ideas get through, i guess i should be grateful one did.
anticholinergic activity is in fact something i am trying to avoid, if amantadine does this...
poster:iforgotmypassword
thread:731690
URL: http://www.dr-bob.org/babble/20070207/msgs/731690.html