Posted by Quintal on February 17, 2007, at 16:48:02
In reply to Re: Antipsychotics+motivation, posted by Klavot on February 17, 2007, at 13:48:19
>If antipsychotics lower dopaminergic activity then why do they have a pro-motivational effect?
You're the first person I've heard to say antipsychotics have a pro-motivational effect. They're notoriously anti-motivational and that's partly why they're used in prisons and psychiatric hospitals to subdue violent and disruptive individuals, not just because of their antipsychotic effect. I suppose some people who have *severe* depression or paralyzing anxiety might find their ability act on their desires improved after those obstacles are removed or reduced somewhat, but it would be a little misleading to extrapolate that into saying antipsychotics are pro-motivational.
Some newer antipsychotic drugs such as Abilify might help motivation, but Abilify has a different effect at D2 receptors being a partial agonist rather than an antagonist.
Q
poster:Quintal
thread:733596
URL: http://www.dr-bob.org/babble/20070213/msgs/733658.html