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Re: Are MAOIs ever ineffective? » Chairman_MAO

Posted by Quintal on February 20, 2007, at 15:27:25

In reply to Re: Are MAOIs ever ineffective? » Quintal, posted by Chairman_MAO on February 20, 2007, at 14:27:31

>Diphenhydramine is safe.

I've read reports to the contrary, and the patient information leaflet 'Nytol One-a-Night' (diphenhydramine 50mg) clearly warns against concomitant use with MAOIs.

>Cyproheptadine can be used to treat serotonin syndrome.

Yes, due to its 5-HT2 antagonism; but Piriton (I guess you were thinking of Periactin?) isn't cyproheptidine, it's chlorpheniramine, which is contraindicated with MAOIs for the reason I stated.

>Those are the big ones to watch out for, aside from centrally-acting decongestants.

I thought these were more likely to cause hypertensive crises than serotonin syndrome?

I agree especially with most of the points in your first post to the thread. I'll reply in more detail soon.

Q


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