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Re: Anyone clued up on dopamine- PLEASE help!!

Posted by itsme2003 on February 21, 2007, at 1:04:23

In reply to Re: Anyone clued up on dopamine- PLEASE help!! » blueberry1, posted by delna on February 18, 2007, at 6:09:16

I've experimented a couple of dopamine agonists as part of an antidepressant cocktail. I've found that they generally contribute to my eating everything in sight. Perhaps it's tied in with a pre-existing serotonin deficiency.

I've tried Cabergoline (Dostinex), Ropinirole (Requip), Amantadine (Symmetrel) and Adderall. It's important to note the different classes of these drugs.

Dostinex is a dopamine agonist. It made me want to eat like crazy.

Requip is a dopamine agonist. It made me want to eat like crazy.

Amantadine is a dopamine releaser and also a reuptake inhibitor (in addition to being an antiviral). I can't remember, but it seemed to me that it was neutral about appetite for me.

Adderall is dopamine reuptake inhibitor (and norepinephrine also). It was an appetite reducer for me although not as much as I would have expected.

Wikipedia speculates that the overeating side effect may be because of its D3 receptor agonist activity.


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