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Re: Drug manufacturing and quality control

Posted by laima on February 26, 2007, at 18:11:36

In reply to Re: Drug manufacturing and quality control, posted by Squiggles on February 26, 2007, at 12:21:30

Well- for me the Barr generic and the Shire brand adderall behave like two entirely different meds: radically different effects, not a matter of potency. So I am not quite "getting" this bioequivalency thing, though I comprehend that's the theory and intention for generics. I'm just not so sure it's always the reality. If the difference in this case was a matter of potency, I could simply take more. Biggest concern: one makes me depressed and feels like speed at times-especially when it suddenly kicks in, then later it ends in a "dump"; the other boosts my mood gently but significantly, and feels like not being on a drug at all-no perceptable anything as it wears off-takes effect so gradually I can't even tell how long after I take it that that is. My doctor is the sole person who is not surprised by any of this, and I'm sorry that I end up feeling defensive about it not just at the numerous pharmacies I visited while hunting for it, but here. It's not my imagination, and I'm not a pharmaceutical industry spokesperson on an anti-generic crusade, nor a mental case perceiving imaginary differences. Sorry there haven't been any answers or clues regarding my big question about who is now specifically calling the shots in the manufacture of the brand version, I guess no one really knows at this point, and really, sorry I mentioned anything at all. Insisting that what I'm experiencing with these meds isn't imaginary only makes me feel worse.


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