Posted by linkadge on March 19, 2007, at 19:47:30
In reply to Current theories must be wrong, posted by FredPotter on March 19, 2007, at 19:00:29
A lot of it is just speculation. Only a portion of studies show that antidepressants increase BDNF in any sustained way.
More recently some have shown that antidepressants increase neuronal turnover more than they do neurogenesis, ie they increase neuronal generation and elimination.
But you are right, what happens after the drug is withdrawn. If any increased signalling capacity was gained, the brain will probably not be able to utilize it. Well hopefully you won't remain like me. Ie. brain perma-f*cked, and unable to respond normally to any pleasurable stimulii.
Antidepressant withdrawl for me, was like experiencing the exact opposite to every positive benifit I gleaned, for about the same length of time as I was on them.
Linkadge
poster:linkadge
thread:742253
URL: http://www.dr-bob.org/babble/20070314/msgs/742269.html