Posted by Deniseuk190466 on March 26, 2007, at 8:29:01
In reply to Re: CRF Antagonists Question » deniseuk190466, posted by Phillipa on March 25, 2007, at 14:23:33
Hi Phillipa,
I'm not sure what I mean either :-)
Well the theory behind CRF antagonists is that people who suffer from depression have high level of cortisol and they have a dysfunctional HPA axis (that's my interpretation anyway). This high level of cortisol is highlighted during the dexamethasone suppression test. When a normal person takes dexamethasone then they should naturally supress cortisol because that is what the drug does but with somebody with high level of cortisol then they don't supress cortisol (that's my understanding anyway).
Well as I did supress cortisol, I was wondering if my cortisol levels and my HPA axis would be regarded as normal and was wondering whether or not I would not respond to one of these Cortisol Releasing Factor drugs.
I don't know, sometimes I'm just searching blindly. I haven't a clue what I'm doing or what I'm talking about :-)
Denise
poster:Deniseuk190466
thread:744121
URL: http://www.dr-bob.org/babble/20070320/msgs/744292.html