Posted by iforgotmypassword on April 2, 2007, at 13:38:04
wondering if myasethenia cholinesterase ihibitors can work similarly to alzheimer's/neurocognitive focused cholinesterase inhibitors.
or if higher doses of neurocognitive focused cholinesterase inhibitors fight the acetylcholine receptor antibody problem in the body.
i am following that lyme antibodies that i test positive for may be related to acetylcholine receptor antibodies. it suggests that lyme antibodies may have varied autoimmune effects, which has already been expected for a range of other symptoms suffered by people that took the vaccine lymerix.
i wish i had the full article but here is the abstract.
oddly, the cholinesterase inhibitor they used (pyridostigmine) does not cross the blood brain barrier, but they noted a resolution "of all remaining neurological defecits."
i know physostigmine does cross the blood brain barrier, and possibly some others, if that would make them even better suited meds.
i had a response to donepezil that was subtle but helpful in ways of being able to express and articulate a little easier, and have little less emotional fogginess. it was fairly subtle tho, and was not a miracle improvement. this response also took a bit of time. going off was noticable.
galantamine would help too, but i fear that made me too driven, but i am not sure what long term would have turned out to be like. initially as opposed to making me feel any more articulate, people just seemed to take me more seriously.
anyway, i am getting an acetylcholine antibody test, and if it is positive, it may be a step toward knowing what may help. in which case i would want to take the drug most likely to help out my mind and get me out of the swamp. i am a little less worried about cholinergic-associated depressive symptoms for me, given my experience with the other meds.
poster:iforgotmypassword
thread:746300
URL: http://www.dr-bob.org/babble/20070402/msgs/746300.html