Posted by polarbear206 on April 5, 2007, at 14:11:02
In reply to Re: Lamictal made me very sick, posted by notfred on April 5, 2007, at 12:31:14
> "SJS is the life threating rash that can ultimately cause a severe systemic reaction and progress to organ failure. There is a 1% chance of this happening. I got a rash when I first started Lamictal, but it went away. I am blonde and have fair skin. More prone to rashes."
>
> The rate is .08% for those taking Lamictal (.8 in 1000) which is 2 orders of magnitude less than 1 %.
>
> It is not even 1% for those taking Lamictal and other anti-sezure meds or with your childern.
> Here are the facts from the monograph:
>
> SERIOUS RASHES REQUIRING HOSPITALIZATION AND DISCONTINUATION OF TREATMENT HAVE BEEN REPORTED IN ASSOCIATION WITH THE USE OF LAMICTAL. THE INCIDENCE OF THESE RASHES, WHICH HAVE INCLUDED
> STEVENS-JOHNSON SYNDROME, IS APPROXIMATELY 0.8% (8 PER 1,000) IN PEDIATRIC PATIENTS (AGE <16 YEARS) RECEIVING LAMICTAL AS ADJUNCTIVE THERAPY FOR EPILEPSY AND 0.3% (3 PER 1,000) IN ADULTS ON
> ADJUNCTIVE THERAPY FOR EPILEPSY. IN CLINICAL TRIALS OF BIPOLAR AND OTHER MOOD DISORDERS, ***THE RATE OF SERIOUS RASH WAS 0.08% (0.8 PER
> 1,000) IN ADULT PATIENTS RECEIVING LAMICTAL AS INITIAL MONOTHERAPY*** AND 0.13% (1.3 PER 1,000) IN ADULT PATIENTS RECEIVING LAMICTAL AS ADJUNCTIVE THERAPY.
Sorry, meant to say < 1%. I am a pychiatric nurse and frankly I have never come accross anyone who experienced this in my 25 years on the job.
poster:polarbear206
thread:747160
URL: http://www.dr-bob.org/babble/20070402/msgs/747249.html