Posted by Quintal on April 23, 2007, at 3:31:53
In reply to Re: Clarity, perception and clear thought » Phillipa, posted by Quintal on April 23, 2007, at 0:18:23
Mechanism of Action:
Nicergoline acts by inhibiting the postsynaptic alpha(1)-adrenoceptors on vascular smooth muscle. This inhibits the vasoconstrictor effect of circulating and locally released catecholamines (epinephrine and norepinephrine), resulting in peripheral vasodilation. Therefore the mechanism of Nicergoline is to increase vascular circulation in the brain, thereby enhancing the transmission of nerve signals across the nerve fibres, which secrete acetylcholine as a neural transmitter.
http://redpoll.pharmacy.ualberta.ca/drugbank/cgi-bin/getCard.cgi?CARD=APRD00617.txt
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poster:Quintal
thread:752472
URL: http://www.dr-bob.org/babble/20070419/msgs/752671.html