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downregulation ace

Posted by FredPotter on May 9, 2007, at 15:24:01

In reply to Re: Please don't kill me guys! zcus, posted by ace on May 9, 2007, at 3:04:07

Anything that increases the availability of a neurotransmitter can poop out. There's more neurotransmitter around so the receptors in the receiving neuron downregulate. The question is: can you reach saturation point where no more downregulation is possible? Presumably the receptors would never switch off completely or we'd die. This line of reasoning would suggest increasing the dose until poop out is no longer possible.
Fred


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poster:FredPotter thread:754567
URL: http://www.dr-bob.org/babble/20070509/msgs/757148.html