Posted by Paulbwell on May 26, 2007, at 23:02:27
In reply to Is methylphenidate a 5-ht2b agonist like fenfluram, posted by linkadge on May 26, 2007, at 18:32:44
"Although binding affinity was not demonstrable at the serotonin (5-HT) transporter site (SERT), novel findings of the study included affinity for the 5-HT1A and 5-HT2B receptor sites for both d- and l-MPH"
This seems to contradict itself,:
-No affinity for 5-ht sites, then
2-Affinity for 5-ht1a, 5ht2b sites.Everythig i'v ever read says Ritalin is a Dopamine and Norphinephrine reuptake inhibitor and a Norph releaser.
Methamphetamine has 5ht releasing properties:
methamphetamine Desoxyn, Methampex, Methedrine, Pervitin, Temmler ADD, ADHD, obesity 10-25mg 10-25 hrs
CYP-2D6 * psychostimulant:
5-HT release +++
NE release +++
DA release ++
DA reuptake inhibition
NE reuptake inhibitionCheers
poster:Paulbwell
thread:759684
URL: http://www.dr-bob.org/babble/20070524/msgs/759731.html