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Olney's Lesions hasn't yet been proved » Quintal

Posted by magicpill on June 9, 2007, at 10:25:42

In reply to Re: amitryptaline and ketamine patch » Phillipa, posted by Quintal on June 8, 2007, at 22:24:57

From the "Controversy" section in the Wikipedia entry:
"There is thus no published evidence at this time (January 2000) that ketamine can produce toxic cell changes in monkeys. The unpublished monkey data that we know about, that of Frank Sharp, actually shows that there is no damage at doses up to 10mg/kg.
White therefore concluded that based on some fundamental differences between rat biology and human biology and because there have only been very few studies done on the occurrence of Olney's lesions, no connection can currently be proved or disproved.[9]"


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URL: http://www.dr-bob.org/babble/20070604/msgs/761983.html