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Re: Grapefruit and Zoloft experiment

Posted by bravohr98 on June 11, 2007, at 3:34:07

In reply to Re: Grapefruit and Zoloft experiment-IMPORTANT, posted by Phillipa on June 8, 2007, at 14:00:04

It does not cause toxic reaction in liver. It blocks cytochrome P450 enzyme CYP3A4 that metabolizes many drugs, including sertraline.

All I know is that it made my zoloft work...

I also found some research data that says Rhodiola also has P450 blocking properties, especially on CYP3A4. It may have drug interactions same as grapefruit.


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