Posted by linkadge on June 16, 2007, at 8:36:50
In reply to Re: The end of Trazodone?, posted by Jedi on June 15, 2007, at 23:58:40
But thats just the blood pressure effect. The effect of valve regurgitation, Ie proliferation of cardiac valve tissue that dammages the valves is a separate issue that may be mediated by 5-ht2b.
The withdrawn dopamine agonists, for instance, were potent 5-ht2b agonists, but not 5-ht2a agonists, yet they had the same effect on heart valves as fenfluramine.
Linkadge
poster:linkadge
thread:763432
URL: http://www.dr-bob.org/babble/20070613/msgs/763540.html