Posted by Jedi on June 18, 2007, at 12:49:38
In reply to See my Pdoc today - PLEA for advice! PLEASE HELP, posted by JerryPharmStudent on June 18, 2007, at 7:22:15
Hi Jerry,
I think you have been on as many combinations as myself. One thing you may not have tried because it is officially contraindicated is a combination of the tricyclic nortriptyline and the MAOI phenelzine. Keep the clonazepam for the anxiety, maybe add a little lithium because it is a proven augmentor and dump the rest of the stuff. Just an idea.
Good luck,
JediPS I see my MD this Friday and think I'm going to drop everything but the clonazepam. I can live with dysthymia, I did for 25 years. If the major depression returns, I'm going to get his assurance that I can go back on phenelzine augmented with lithium.
References:
A 3-year follow-up of a group of treatment-resistant depressed patients with a MAOI/tricyclic combination.
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=7560546&ordinalpos=38&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumTreatment response of depressed outpatients unresponsive to both a tricyclic and a monoamine oxidase inhibitor antidepressant.
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=8071301&ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumCombined MAO-inhibitor and tri- (tetra) cyclic antidepressant treatment in therapy resistant depression.
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=3406429&ordinalpos=16&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum
poster:Jedi
thread:763880
URL: http://www.dr-bob.org/babble/20070613/msgs/763927.html