Posted by linkadge on July 3, 2007, at 11:15:46
In reply to Re: Progressive loss of grey matter in Schizophrenia, posted by Klavot on July 3, 2007, at 9:46:55
>Regarding drugs that promote neurogenesis, could >it be that these drugs lead to greater BDNF in >the brain simply because the brain is trying to >protect itself against a perceived chemical >assault from the drugs?
In most cases, thats what (I think) is probably happenening. Many of the BDNF studies only look at short term administration of antidepressants etc. Wheather or not SSRI's increased BDNF a year later is the question. I wouldn't be suprised to find BDNF at pretreatment levels after such time.
And like you say, the brain does release BDNF in response to potential threats. Ie exercise, fasting, seizures, brain injury etc.
After head injury, BDNF levels are VERY high.
Linkadge
poster:linkadge
thread:767217
URL: http://www.dr-bob.org/babble/20070630/msgs/767375.html