Posted by Racer on July 4, 2007, at 16:43:44
In reply to Re: Why shouldn't Zoloft be taken with Synthroid o, posted by Glydin on July 4, 2007, at 10:15:21
> POSSIBLE interactions also can include potentiation or a dampening of one or both med's effects. This could be with absorption or with assimilation due to liver or chemical pathways... and it's not always a given that it will occur in every person. And it may just mean adjustments in dose or ingestion.
>
> Drugs whos results are the same and are of the same class can use different modes of action to achieve the desired results, so, no not all drugs in a class are the same. Nor does everyone's body respond the same..... If so... probably there would be only need for one of everything.Absolutely! The SSRIs are all different drugs, thus the different names, right? ;-)
And the interaction between Synthroid and Zoloft is dosage related. According to RxList.com,
"Administration of sertraline in patients stabilized on levothyroxine may result in increased levothyroxine requirements."
So, the warning sounds as though they're recommending other SSRIs first, so that you don't have to change the dosage on someone who's stable on Synthroid already.
Hope that helps. And it's good to see your name again.
poster:Racer
thread:767525
URL: http://www.dr-bob.org/babble/20070630/msgs/767653.html