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Re: Tolerance to Benzo Anxiety Effects - dopamine?

Posted by Quintal on August 19, 2007, at 16:42:08

In reply to Re: Tolerance to Benzo Anxiety Effects - dopamine? » FredPotter, posted by Squiggles on August 19, 2007, at 15:31:57

Benzos aren't the same as alcohol, but they exert most of their effects on the GABA system, like alcohol. Alcohol also binds to the GABA-A benzodiazepines receptors. In a sense, benzos are 'cleaner' than alcohol because alcohol binds to many other receptors and is quite noxious to many organs/systems.

I've drunken huge quantities of alcohol with hefty doses of Klonopin before and had no problems, but that doesn't mean other people haven't. I think most fatalities have been due to overdosing on extreme polypharmacy though, such as Heroin + overdose of benzos combined with a few bottles of Whiskey. Benzos enhance the effect of alcohol, but at truly moderate amounts of both there should be no problem for healthy people provided they follow the usual precautions and don't operate heavy machinery or perform skilled tasks under the influence.

Q


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