Posted by Squiggles on September 27, 2007, at 15:46:32
In reply to Re: I seek permanent hypomania., posted by linkadge on September 27, 2007, at 12:04:13
> >Every medicine develops tolerance. Euphoric >effects may be related to dopaminergic activity >in the nucleus accumbens, to which you develop a >tolerance extremely quickly.
>
> >Must I trick a doctor into giving me an >electrode, hide the euphoria from them while >it's implanted? Yes.
>
> You're seeking bipolar gene expression. No doctor would implant an electrode directly into your Neucleus accumbens. I don't think this is what DBS does.
>
> Even so, rat experiments show that they will develop tollerance to threshold electrical stimulation of the neucleus accumbens.
>
> It is *too* hard wired. It is impossable to think your way around it. Its got feedback loops on its feedback loops.
>
> It is the nature of human to believe he can achieve perpetual happiness, but your brain would never let you get there as then nothing else would matter.
>
> Linkadge
>I don't know much about biology, but i have noticed that sensory and perceptual information processing works very much like electrical switches: for example, when a saturation point of stimulation is reached in the senses, the organ switches off, and requires a set time to revive.
An example, would be bright lights' threshold and time needed to recover pre-stimulation state.I've wondered if it is possible that manic-depressive states may follow a similar principle. But that is just an analogy and i guess the whole brain would not work the same way as sensory apparatus.
A permanent steady state is probably not possible even in a coma. Only death as far as we know-- maybe that's why they say "rest in peace".
Squiggles
poster:Squiggles
thread:785240
URL: http://www.dr-bob.org/babble/20070919/msgs/785542.html