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Re: Abilify's effect on depressive symptoms? » Phillipa

Posted by psychobot5000 on September 29, 2007, at 13:26:40

In reply to Re: Abilify's effect on depressive symptoms?, posted by Phillipa on September 25, 2007, at 10:51:39

> I thought it was atypical antipsychotic so how does it do all these other things? Thought it was stimulating? Phillipa

The thing researchers seem to focus on is that, unlike most other atypical antipsychotics, it's a D2 partial agonist, rather than a D2 antagonist. So possibly because of that, one can get some dopaminergic benefits, similar to D2 agonists like pramipexole, as well as antipsychotic control... Its efficacy for motivation and such in some people seems to support the idea, as I understand the situation.

For me it just made my head cloudy.


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