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Re: Which drugs are the most neuroprotective?

Posted by linkadge on October 5, 2007, at 23:06:28

In reply to Re: Which drugs are the most neuroprotective? » linkadge, posted by Squiggles on October 5, 2007, at 21:15:41

>But once over the therapeutic level, or just
>downright too high like any other drug, the
>memory gets affected and you get spacey when
>toxic.

Yes there is an excitotoxic nature to lithium. If you take too much too soon you can have glutamate neutoxocity as well. Acutely, lithium actually dramatically lowers glutamate reuptake resuliting in high levels of glutamate, but chronically it forces glutamate into a very narrow theraptutic index.

>Otherwise, i think it does
>enhance cognitive ability; whether that is due
>to the equillibration of emotions or a direct
>neurological effect,

I found it definately slowed me down. It didn't make me dumb, it just slowed me down.

>i don't know. BTW, i think
>the kidney tale is a psycho-urban hyperbole-- it >may depend on dose and conditions, just like >other drugs.

I dunno. That seems like wishfull thinking. I think the kidney issues are fiarly well established documented. Not everybody develops significant issues, but..

Linkadge


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URL: http://www.dr-bob.org/babble/20070929/msgs/787169.html